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*******The Scientific Bit*******
***The Product***
Reductil (U.S. name Meridia) (Sibutramine) is a drug most commonly used for weight loss. It contains the active ingredient Sibutramine Hydrochloride Monohydrate, which was first manufactured as an antidepressant. Reductil comes in 10mg and 15mg strengths. The 10mg capsules are blue/yellow and have Reductil 10 printed on them. The 15mg capsules are blue/white and have Reductil 15 printed on them. Both strengths come in blister packs, in boxes of 28 capsules.
***Other Ingredients***
Dimeticone, Iron oxides and hydroxides (E172), gelatine, colloidal anhydrous silica, indigo carmine (E132), lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium lauryl, sulphate, shellac, soybean lecithin (E322), titanium dioxide (E171). The 10mg capsule also contains Quinoline yellow (E104).
***The Criteria***
Reductil is a prescription only medication which comes with certain criteria. To be eligible for use you need to fall into one of two categories.
*Have a body mass index of 27 or over and has diabetes.
It is possible to buy this medication online(UK) - however it is expensive (starting at £100 for a months supply) and you have to have an online consultation with a GP. It is available in the US online, but you can't guarantee that you are getting the genuine medication. I wouldn't advise buying this medication online but to seek advise from your GP.
***What
it does***
Reductil is an appetite suppressant. If works by making the body feel satisfied after eating less food. By eating less food you should be able to lose weight. It also raises your metabolic rate (how quickly your body burns energy) which also speeds up the weigh loss process.
***Warnings***
For some people, this method of weight loss is not suitable. Anyone with the following problem/conditions should consult with their GP before taking this medication.
* if you have ever had any eating disorder including anorexia/bulimia
* if you have had a psychiatric illness or have taken drugs to treat this or depression in the last 2 weeks
* if you have glaucoma
* if you have a drug or alcohol problem
* if you have a medical condition which causes your weight gain
Most of these your GP will be aware of, but it is best to discuss it with him beforehand in case he has forgotten. GP’s are human too!
***Taking Reductil***
Whilst you are taking Reductil, you will be monitored closely by your GP. Your weight and blood pressure should be checked at least once a fortnight. Reductil can cause blood pressure to rise and in this case you may be taken off the medication.
It is best to avoid alcohol whilst taking Reductil. Alcoholic drinks are high in calories and contain no goodness; however the odd glass of wine will do you no harm.
Sometimes Reductil (as with any medications) can affect your judgement. It is best to see how you are affected before driving and/or operating machinery. If you have to use machines or drive as part of your job, it would be wise to advise your employer so they can put you on light duties while you are adjusting to the medication.
Reductil should be taken first thing in the morning. You can take it with or without food but it must be swallowed whole with plenty of water.
If you forget to take a dose, don’t double up. Carry on the following day as usual.
If you take too many capsules, consult your GP/A&E department immediately. Make sure you have the box with you so you can tell/show them the exact ingredients.
You should continue to take Reductil until your GP advises to stop.
If you don’t lose weight or gain weight in the first three months, your GP will probably take you off the medication. Reductil isn’t normally prescribed for more than a year.
***Taking with other medications***
Some medications do not mix with Reductil. If you are taking any of the following, make sure you discuss it with your GP. He may stop the other medication whilst you are on Reductil, or he may decide that Reductil is not for you.
* Some antibiotics: Rifampicin, Erythromycin and Clarithromycin
* Some epilepsy medicines: Carbamazepine, Phenobarbital, Phenytoin
* The antifungal medicines: Ketoconazole and Itraconazole
* Some migraine medicines: Sumatriptan and Dihydroergotamine
* Some painkillers: Fentanyl, Pentazocine, Pethidine and Dextromethorphan
* Some steroids: Cyclosporin and Dexamethasone
* Anti-coagulants: Heparin and Warfarin
*Remember that some over-the-counter medicines/remedies can also have affects – make sure you consult your GP about these before taking Reductil*
***Side Effects***
Common side effects (affecting 10 in every 100) are:
* Loss of appetite, constipation, dry mouth and problems sleeping.
Other Common side effects (affecting in-between 1 and 10 in every 100) are:
* Fast heartbeats, palpitations, abnormal heart rhythm, raised blood pressure, hot flushes, feeling sick, haemorrhoids worsening, sweating, funny taste in mouth, light-headedness, pins and needles, headaches, feeling anxious.
Uncommon side effects (affecting less than 1 in every 100) are:
* kidney problems, raised levels of liver enzymes, purple rash on legs, bruising, seizures, blurred vision, depression, suicidal thoughts, feeling restless, hair loss, short term memory loss, impotence and menstrual disorders.
*If you suffer any of these side effects – you should stop taking Reductil immediately and consult your GP*
*******My Experience*******
So I’ve given you all the science stuff, here’s my experience of Reductil.
After giving up smoking (there’s another review sometime!), I found I’d gained a fair bit of weight. Well 3 stones to be precise. I don’t know how it happened, I didn’t eat any more than I had previously and it seemed to appear really quickly. I can only assume that my metabolic rate plummeted and ground to a halt. I tried numerous ways to lose the excess weight but it wouldn’t shift. After approx 2 and a half years of trying and only 6lbs lighter, my GP agreed to let me try Reductil. Although I didn’t fit into either of the Criteria categories, he sympathised with my plight and sent me on my way with the magic prescription……………………………..
First things first, it’s not a miracle cure. You actually have to watch what you put into your mouth. If you take the Reductil and then sit and eat crisps and chocolate all day, it’s not going to work. You have to change your eating habits and your lifestyle to be able to lose weight and keep it off.
I started taking the Reductil around 8am in the morning. For the first two days I felt no different. Day 3 came and went and I realised that I hadn’t actually eaten all day. This became the norm; I had to force myself to eat. The part of my brain which said “I’m hungry” had gone completely. The part of my brain which said “Sleep” also went and I found myself almost in “hyper mode” 24/7. Changing the dosage time to 5/6am helped a great deal and I found myself being able to sleep for a few hours a night. In the first 2 weeks of being on Reductil I had lost over a stone in weight.
My GP was delighted with my progress. My blood pressure was checked and all was well. He referred me to the Gym (within the surgery) where I spent 3 hours a week with a personal trainer advising me on the best exercise regime.
Other than the forgetting to eat and insomnia I had no other side effects. After being on Reductil for 6 months, I had gone from 11st 12lbs to 8st 11lbs. Yup, I’d lost 3st 1lb. Dress size went from a size 12/14 to a size 8 and I felt amazing. I came off the medication quite easily, not suffering any withdrawal symptoms.
You may think that this is the end of my experience? I wish it was. Within 2 years I have gained most of the weight back. I’m not entirely sure if this is a side effect of coming off the drug. It’s more likely that due to my marriage break up I became withdrawn and lazy and consoled myself with comfort eating. I stopped going to the gym and all my motivation disappeared.
So here I am, taking Reductil again. This time is different however, I don’t have the same “hyper mode” feelings, I’m sleeping fine and I am remembering to eat. The weight is not coming off as easily this time either and I’m having to work really hard to lose every lb.
Would I recommend Reductil??? Yes I would. But remember you have to put the effort in. The drug can only do so much. You have to change your way of thinking, your lifestyle and find an exercise routine that you can continue once the medication stops.
*** 22/05/2007 – Current Weight – 11stone***
I will update when the scales say nice things to me :-)
Thanks for reading, Lisa xxx
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Interesting review - I know someone who used this to lose weight prior to conceiving and it worked, but she did put it back on again eventually
carcraig 15.02.2008 22:54
Great review...I can't believe you dropped a whole stone in 2 weeks... I found that relationship break-ups had the opposite effect on me, that was when I always lost weight! Caroline xx
JunePixie 21.12.2007 11:44
I think in your review you mentioned all the elements needed to lose and keep weight off. The drugs don't work, it just makes it worse! 1) East sensible 2) Eat in moderation, i.e; cut back on everything but don't cut out anything. 3) Gym or whatever 4) Willpower.